Product Name :
Azide-PEG3-Tos
Description:
Azide-PEG3-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Azide-PEG3-Tos is also a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
CAS:
178685-33-1
Molecular Weight:
329.37
Formula:
C13H19N3O5S
Chemical Name:
1-({2-[2-(2-azidoethoxy)ethoxy]ethoxy}sulfonyl)-4-methylbenzene
Smiles :
CC1=CC=C(C=C1)S(=O)(=O)OCCOCCOCCN=[N+]=[N-]
InChiKey:
PTOJCKLTCKYNFG-UHFFFAOYSA-N
InChi :
InChI=1S/C13H19N3O5S/c1-12-2-4-13(5-3-12)22(17,18)21-11-10-20-9-8-19-7-6-15-16-14/h2-5H,6-11H2,1H3
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Azide-PEG3-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Azide-PEG3-Tos is also a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).|Product information|CAS Number: 178685-33-1|Molecular Weight: 329.37|Formula: C13H19N3O5S|Chemical Name: 1-({2-[2-(2-azidoethoxy)ethoxy]ethoxy}sulfonyl)-4-methylbenzene|Smiles: CC1=CC=C(C=C1)S(=O)(=O)OCCOCCOCCN=[N+]=[N-]|InChiKey: PTOJCKLTCKYNFG-UHFFFAOYSA-N|InChi: InChI=1S/C13H19N3O5S/c1-12-2-4-13(5-3-12)22(17,18)21-11-10-20-9-8-19-7-6-15-16-14/h2-5H,6-11H2,1H3|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Bortezomib} site|{Bortezomib} Metabolic Enzyme/Protease|{Bortezomib} Technical Information|{Bortezomib} Data Sheet|{Bortezomib} manufacturer|{Bortezomib} Epigenetics} |Shelf Life: ≥12 months if stored properly.{{Lenalidomide} MedChemExpress|{Lenalidomide} Molecular Glues|{Lenalidomide} Technical Information|{Lenalidomide} Purity|{Lenalidomide} supplier|{Lenalidomide} Cancer} |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:33135387 |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.|Products are for research use only. Not for human use.|
